#3   
April 2010  
EASL 2010 meeting:
To See FibroMeters’ communication posters
 
  FibroMeters: blood tests for liver fibrosis
 
FibroMeters are performed by calculations of scores obtained from clinical data and blood laboratory results.

FibroMeters are performant because they offer:

 
A specific version for the main causes of chronic liver diseases(virus, alcohol, NAFLD);
  An evaluation of the score AND the percentage of liver fibrosis;
  An expert system detecting and correcting discordant biological markers.

EASL2010Compteurs_1.png

FibroMeters are validated by the French Health Authority in untreated adult patients with Hepatitis C without comorbidity.
 
 
  Five abstracts on FibroMeters were presented during the 2010 EASL meeting

 Fibrosis and hepatic steatosis

NON-INVASIVE DIAGNOSIS OF LIVER LESIONS BY BLOOD TESTS IN NAFLD
(P. Calès et al) (P.334)

All the main histological liver lesions (fibrosis and steatosis) in NAFLD can be correctly non-invasively quantified.
This abstract has been awarded as top 10% of posters during the EASL congress 2010.
See poster

 FibroMeter’s performance

ACCURACY OF LIVER FIBROSIS CLASSIFICATIONS PROVIDED BY NON-INVASIVE TESTS
(P. Calès et al) (P.1048)

By using classifications into fibrosis stages instead of a binary diagnostic (presence or not of significant fibrosis), the diagnostic accuracy of test classification is significantly better with FibroMeter compared to the other tests. This performance allows to the FibroMeter a reliable diagnostic up to 80% in 100% of patients without liver biopsy.
See poster


ROBUSTNESS AND OPTIMIZATION OF AN ACCURATE BLOOD TEST FOR LIVER FIBROSIS
(P. Calès et al) (P.1049)

The diagnostic accuracy of a new FibroMeter without hyaluronate, nearly twice less expensive than the former version, is excellent regarding significant fibrosis and cirrhosis.
See poster

 Co-infection

COMPARISON OF LIVER FIBROSIS BLOOD TESTS DEVELOPED FOR HCV WITH NEW SPECIFIC TESTS IN HIV/HCV CO-INFECTION
(P. Calès et al) (P.1047)

Non-invasive tests designed for hepatitis are less performant in HIV/HCV infections. Specific FibroMeter for co-infection has shown higher performance than standard tests constructed for mono-infected patients; this FibroMeter will be marketed in 2010.
See poster

 Combination with Fibroscan

A NEW FIBROSIS STAGING METHOD PROVIDES VERY ACCURATE NON-INVASIVE DIAGNOSIS OF LIVER FIBROSIS WITHOUT LIVER BIOPSY
(J. Boursier et al) (P.1046)

The non-invasive diagnosis of liver fibrosis in patients with hepatitis C is improved by a combination of FibroMeter with Fibroscan. A new combining fibrosis stage classification provides a diagnosis in 100% of patients with 88% accuracy without any liver biopsy.
See poster
 
 
  Practical aspects
 
Scientific information
 
How to prescribe the FibroMeters?

See on our website www.biols.com

or contact us by phone: +33 2.41.36.07.19
   
BioLiveScale Faculté de médecine - Rue Haute de Reculée - 49045 Angers Cedex - contact@biols.com
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